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Effect of Delay in Thrombectomy Reperfusion on Patient Outcome After Acute Ischemic Stroke

This study is aimed at investigating variables in combination recanalization therapies for acute, large vessel ischemic stroke that are associated with better clinical outcomes (measured by NIH stoke scale and modified Rankin Scale). Identification of these variable could potentially improve treatment guidelines and reducing morbidity in the elderly population who are disproportionately affected by stroke. Specific aims of the study include: *Determine the effects of delay in reperfusion on patient outcome after thrombectomy for acute ischemic stroke 6-24 hours after stroke onset. *Determine if other factors such as age, gender, extent of imaging perfusion and diffusion mismatch indicating the presence of penumbra (salvageable brain tissue), and the anesthetic techniques used influence patient outcome in patients receiving thrombectomy treatment 6-24 hours after stroke onset.

This study is aimed at investigating variables in combination recanalization therapies for acute, large vessel ischemic stroke that are associated with better clinical outcomes (measured by NIH stoke scale and modified Rankin Scale). Identification of these variable could potentially improve treatment guidelines and reducing morbidity in the elderly population who are disproportionately affected by stroke. Specific aims of the study include: *Determine the effects of delay in reperfusion on patient outcome after thrombectomy for acute ischemic stroke 6-24 hours after stroke onset. *Determine if other factors such as age, gender, extent of imaging perfusion and diffusion mismatch indicating the presence of penumbra (salvageable brain tissue), and the anesthetic techniques used influence patient outcome in patients receiving thrombectomy treatment 6-24 hours after stroke onset.